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Cake day: October 25th, 2023

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  • As someone who’s graduating in biotechnology, we want and we do, but there are a few things that make this not reach the market.

    Round-up ready plants are incredibly easy to make, you insert only one gene (effectively, there are some little extra things but details) and now your plant can resist glyphosate, which means you can make many different species resistant to it much more easily, or make all of the different lines of whatever crop you sell also be restaurant to it.

    For making drought resistant plants, there isn’t exactly one gene that makes the plant resistant. Just one example would be root length. If a plant has longer roots it can access moist soil for longer periods of time and thus making it more resilient against droughts, but to make the roots grow longer you have several genes that interact and changing one might not result in deeper roots in a drought environment since that gene is activated by a phytohormone that is upregulated during long days (summer time) but this location only encounters droughts during early spring when the days are still short, and for you to regulate that gene to change when the phytohormone is upregulated you’d need to change a BUNCH of other things on the plant that would result in a complete mess of how the plant develops as now it acts like summer during spring but only for the roots and the roots send signals that the leafs must ignore until the correct time of the year and that changes when the seeds are going to be released because the plant is now blooming at a completely different time and oh fuck we’ve developed the equivalent of ancient Egyptian inbreed pharaohs but for plants, which is horrible but incredibly impressive given that most plants can self fertilize… This is one route of trying to just make longer roots, if we go through giving the root growth gene sensibility to another phytohormone that is upregulated on short days, the roots now will release other phytohormones in higher levels than the plant is used to (more length = more roots = more cells making said phytohormones) and since plants develop through gradients of hormones and the proportion of one vs another, the amount of work to make it so that the plant actually develops correctly will also be huge! And this is just for one single characteristic that we think would help in many cases but wouldn’t actually make plants fully resistant to droughts, just able to get a few extra days of water, unlike how roundup ready is still just add this gene that allows the plant to break down glyphosate fast enough that it doesn’t die.

    Now the other side of the issue is funding. Yeah, droughts are a really bad problem for farms, but the BUG farms are either in places that they don’t suffer from droughts that much, in places that they can buy a lot of water cheaply (government subsidies) or can produce a lot of crops even when there’s a drought vs what they’d loose against weeds competing with their crops for water, nutrients and diseases spread by those weeds

    In the end, we have the same reasons that tuberculosis and malaria are not funded and researched flash much as they should, it just doesn’t make sense (commercially) to do so for big corporations like monsanto/bayer and the subject is complex enough that several universities having small teams researching it will tackle it from so many different angles and have such a difficult time with it that progress is really slow. The researchers want to work on cures for malaria, tuberculosis and to make plants resistant to droughts, soil acidification, nutrient content of the final produce and much much more, but we’re fighting against capitalism and spaghetti code with no annotations written by thousands of not millions of different coders that didn’t talk with each other through the millions of years of development of said code


  • argarath@lemmy.worldtoCasual UK@feddit.ukDiscuss
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    6 months ago

    I’ll start saying I’m Brazilian and have never gone to the British islands, but I feel like this is wrong just by beef Wellington being so low. I’ve had a homemade one and it was the best thing ever, and even before having it, it just sounds so delicious!!! Anyway besides that everything above the lowest tier are def on my list of things I’d love to try at least once, while some of the lowest tier just make me not want to try because of the idea of what bit of meat I’d be eating, I would give it a try since I do enjoy a bit of liver every know and then, and chicken hearts are really good (at least in the Brazilian BBQ style) so I could like boss sausages and other things





  • Hi, I am graduating in biotechnology and my professors discussed this in class. The main points they brought up were:

    1: the technique used for gene editing in those test subjects was and still is not 100% specific. With the correct primers you can still have incorrect breaks in the DNA and incorrect adhesion of your gene of interest, pair of bases can be lost and/or introduced indirectly, causing mutations that range from luckily encoding the same aminoacid to a sequence break, altering all of the following aminoacids and resulting in either a truncated protein that luckily does nothing to a protein that results in who knows what damage to the cell. This is ok in situations where you’re changing just a few calls inside or outside of the body, but when you’re changing the genome of an entire person, that is extremely dangerous for no real gain because

    2: the gene he edited was still being studied and was not guaranteed to give them immunity and it turned out they didn’t gain immunity to HIV.

    3: there are better ways to guarantee a baby is not born with HIV that are better known, do not involve possibly giving ultra cancer to babies and have been throughout tested before, they did not advance our scientific knowledge and put people’s lives in danger for no guaranteed benefit besides his own ego.

    There’s a reason why the entire scientific community was against his actions, especially those who work with genetic editing.








  • argarath@lemmy.worldtoScience Memes@mander.xyzugh i wish
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    1 year ago

    Agreed with everything you said. I had a class about bio processes and one of them was about production of cheese and during the class both our professor and the scientist that was walking us through the chemistry of cheese making were constantly talking how pasteurization was really good for us all and how annoying it was that it made cheese making more difficult because of the way it messed with casein and other proteins, making it so that the cheese wouldn’t “coagulate” correctly (they used a specific term that I cannot remember for the life of me, sorry) but that was all. A protein being bent up a bit doesn’t negatively affect the milk of where just drinking it or using it to bake, Ave even for cheese making there are tequiniques to still make it into cheese with pasteurized milk.




  • Windows. I am tired of the constant enshitification. I was waiting for it’s end of support because of games and the extra work needed to make them work on Linux (had to have the support of two friends who know Linux to try and get my steam to actually recognize my games and run them with proton, and it took 3 nights of help to find the issues and then fix them to get it working consistently) but I am so glad I’m doing this now, I’m already enjoying Linux more than windows and the issues I’m having are because of companies like discord not making streaming unnecessarily a pain